Elsevier’s Integrated Review Biochemistry, 2nd Edition

Chủ biên: John W. Pelley

Nhà xuất bản: ELSEVIER, Saunders

Năm xuất bản: 2012

Ngôn ngữ: English

Effectively merge basic science and clinical skills with Elsevier’s Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com – included with your purchase – allows you to conveniently access the book’s complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation.

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Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response.

Tác giả: World Health Organization

Sir John Crofton (1912–2009), whose pioneering work in the use of combination drug therapy for the treatment of tuberculosis has resulted in countless lives saved

“The greatest disaster that can happen to a patient with tuberculosis is that his organisms become resistant to two or more of the standard drugs. Fortunately we can prevent the emergence of drug resistance in virtually all cases if we take enough trouble to ensure that the best drug combinations are prescribed and that the patient takes them as directed. It is often not realized how venial a sin can result in ultimate disaster. It might be suggested that giving a risky combination of drugs, or even giving a drug alone, will not matter if it is only for a short time. It is true that it may not matter in a number of patients, but in some it can matter very much and may make all the difference between survival and death.

The development of drug resistance may be a tragedy not only for the patient himself but for others. For he can infect other people with his drug-resistant organisms. In such patients the disease would not be sensitive to the drug in question. A recent survey by the Medical Research Council (Fox et al., 1957) in various clinics all over the country has shown that no less than 5% of newly diagnosed patients were infected with organisms resistant to at least one of the three main drugs. If physicians come to apply thoroughly the present knowledge about preventing drug resistance, this percentage should steadily diminish”.

From Chemotherapy of pulmonary tuberculosis, by John Crofton, read to a plenary session at the Annual Meeting of the British Medical Association, Birmingham, England, 1958 (British Medical Journal, 1959, 5138(1):1610–1614).

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